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Abstract
X-ray-based analytics are routinely applied in many fields, including physics, chemistry, materials science, and engineering. The full potential of such techniques in the life sciences and medicine, however, has not yet been fully exploited. We highlight current and upcoming advances in this direction. We describe different X-ray-based methodologies (including those performed at synchrotron light sources and X-ray free-electron lasers) and their potentials for application to investigate the nano-bio interface. The discussion is predominantly guided by asking how such methods could better help to understand and to improve nanoparticle-based drug delivery, though the concepts also apply to nano-bio interactions in general. We discuss current limitations and how they might be overcome, particularly for future use in vivo
Item Type: | Journal Article |
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Publication: | ACS Nano |
Publisher: | American Chemical Society |
Additional Information: | The copyright for this article belongs to the Authors. |
Keywords: | Chemical analysis; Drug delivery; Electrons; Free electron lasers; Synchrotron radiation; X ray lasers, Biointerfaces; Current limitation; In-vivo; Life-sciences; Synchrotron light source; X-ray free electron lasers, X rays, nanoparticle, laser; radiography; synchrotron; X ray, Lasers; Nanoparticles; Radiography; Synchrotrons; X-Rays |
Department/Centre: | Division of Physical & Mathematical Sciences > Physics |
Date Deposited: | 15 May 2023 09:16 |
Last Modified: | 15 May 2023 09:16 |
URI: | https://eprints.iisc.ac.in/id/eprint/81463 |
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