Ionic liquid-assisted fabrication of poly(vinyl alcohol)/nanosilver/graphene oxide composites and their cytotoxicity/antimicrobial activity

Sahu, G and Das, M and Sethy, C and Wazalwar, R and Kundu, CN and Raichur, AM and Tripathy, J (2021) Ionic liquid-assisted fabrication of poly(vinyl alcohol)/nanosilver/graphene oxide composites and their cytotoxicity/antimicrobial activity. In: Materials Chemistry and Physics, 266 .

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Abstract

Antimicrobial materials with enhanced mechanical and thermal properties must be developed for innovative applications in medicine, food and packaging, etc. This study presents ionic liquid-assisted fabrication of graphene oxide, silver nanoparticles and poly(vinyl alcohol) based composite films (PVA/Ag/GO-IL) for antibacterial applications. The morphological, structural, thermal and mechanical characteristics of the nanocomposite films were investigated and compared with PVA/Ag/GO nanocomposite films fabricated without using ionic liquid. The presence of ionic liquid enhanced the dispersion of nanofillers in PVA matrix and improved the mechanical and thermal properties. Further, investigations were carried to assess the antibacterial and cytotoxic properties of the samples. The antibacterial tests of nanocomposite films were performed on Escherichia coli and Staphylococcus aureus using two different methods. The results showed superior antibacterial activity of PVA/Ag/GO-IL nanocomposite films as compared to PVA/Ag/GO and PVA/Ag films. The PVA/Ag/GO-IL and PVA/Ag/GO nanocomposites exhibited low cytotoxicity on MCF-7, MDA-MB-231(cancer cell lines) and MCF-10A (human epithelial cell line) indicating good biocompatibility. © 2021 Elsevier B.V.

Item Type:	Journal Article
Publication:	Materials Chemistry and Physics
Publisher:	Elsevier Ltd
Additional Information:	The copyright for this article belongs to Elsevier Ltd.
Keywords:	Biocompatibility; Cell culture; Escherichia coli; Fabrication; Graphene oxide; Ionic liquids; Nanocomposite films; Nanocomposites; Packaging materials; Polyvinyl alcohols; Silver compounds; Silver nanoparticles; Thermodynamic properties, Ag++; Anti-bacterial activity; Cytotoxicity study; Graphene oxides; Mechanical and thermal properties; Poly (vinyl alcohol) (PVA); Poly(vinyl alcohol); Poly(vinyl alcohol) (PVA); Polymer nanocomposite; Polymer-nanocomposite, Cytotoxicity
Department/Centre:	Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy)
Date Deposited:	08 Mar 2023 09:14
Last Modified:	08 Mar 2023 09:14
URI:	https://eprints.iisc.ac.in/id/eprint/80823

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