An Overview of Dps: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties

Williams, SM and Chatterji, D (2021) An Overview of Dps: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties. [Book Chapter]

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Abstract

DNA binding proteins under starvation (Dps) are proteins belonging to the ferritin family with the capacity for DNA binding, in addition to iron storage and ferroxidation. Present only in the prokaryotes, these multifaceted proteins have been assigned with a number of roles, from pathogenesis to nucleoid condensation and protection. They have a significant role in protecting the cells from free radical assaults, indirectly by sequestration of iron and by directly binding to the DNA. Due to their symmetry, stability and biomineralization capacity, these proteins have ever increasing potential applications in biotechnology and drug delivery. This chapter tries to bring together all these aspects of Dps in the view of current understanding and older perspectives by studies of our group as well as other experts in the field.

Item Type:	Book Chapter
Publication:	Subcellular Biochemistry
Publisher:	Springer Science and Business Media B.V.
Additional Information:	The copyright for this article belongs to Springer Science and Business Media B.V.
Keywords:	Atomic force microscopy; DNA binding proteins; Ferritin family; Iron oxidation; Nanovehicles
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	20 Apr 2023 06:07
Last Modified:	20 Apr 2023 06:07
URI:	https://eprints.iisc.ac.in/id/eprint/80642

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