ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

How Reliable are Test Numbers for Revealing the COVID-19 Ground Truth and Applying Interventions?

Gopalan, A and Tyagi, H (2020) How Reliable are Test Numbers for Revealing the COVID-19 Ground Truth and Applying Interventions? In: Journal of the Indian Institute of Science, 100 (4). pp. 863-884.

[img]
Preview
PDF
jou_ind_ins_100-4_863-884_2020.pdf - Published Version

Download (3MB) | Preview
Official URL: https://doi.org/10.1007/s41745-020-00210-4

Abstract

The number of confirmed cases of COVID-19 is often used as a proxy for the actual number of ground truth COVID-19-infected cases in both public discourse and policy making. However, the number of confirmed cases depends on the testing policy, and it is important to understand how the number of positive cases obtained using different testing policies reveals the unknown ground truth. We develop an agent-based simulation framework in Python that can simulate various testing policies as well as interventions such as lockdown based on them. The interaction between the agents can take into account various communities and mobility patterns. A distinguishing feature of our framework is the presence of another ‘flu’-like illness with symptoms similar to COVID-19, that allows us to model the noise in selecting the pool of patients to be tested. We instantiate our model for the city of Bengaluru in India, using census data to distribute agents geographically, and traffic flow mobility data to model long-distance interactions and mixing. We use the simulation framework to compare the performance of three testing policies: Random Symptomatic Testing (RST), Contact Tracing (CT), and a new Location-Based Testing policy (LBT). We observe that if a sufficient fraction of symptomatic patients come out for testing, then RST can capture the ground truth quite closely even with very few daily tests. However, CT consistently captures more positive cases. Interestingly, our new LBT, which is operationally less intensive than CT, gives performance that is comparable with CT. In another direction, we compare the efficacy of these three testing policies in enabling lockdown, and observe that CT flattens the ground truth curve maximally, followed closely by LBT, and significantly better than RST. © 2020, Indian Institute of Science.

Item Type: Journal Article
Publication: Journal of the Indian Institute of Science
Publisher: Springer
Additional Information: The copyright for this article belongs to the Author(s).
Keywords: Computer software; Population statistics, Agent based simulation; Contact tracing; Location based; Long distance interactions; Mobility datum; Mobility pattern; Simulation framework; Testing policy, Well testing
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Date Deposited: 11 Jan 2023 11:42
Last Modified: 11 Jan 2023 11:42
URI: https://eprints.iisc.ac.in/id/eprint/79053

Actions (login required)

View Item View Item