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Chemical synthesis of small-ring cyclic oligosaccharides

Maiti, K and Samanta, GC and Jayaraman, N (2020) Chemical synthesis of small-ring cyclic oligosaccharides. In: Arkivoc, 2021 (4).

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Official URL: https://doi.org/10.24820/ARK.5550190.P011.345

Abstract

Immense interest on studies and applications of naturally-occurring cyclic oligosaccharides has attracted novel methods and ingenuities in their chemical synthesis. The conformation of the monosaccharides constituting the macrocyles is important, in order to permit cyclization and facilitate the macrocyclic supramolecular properties. Synthesis of small-ring cyclic oligosaccharides combining the structural and functional features continues to be a challenge. This review article assesses the current chemical methods for the synthesis of small-ring cyclic oligosaccharides, particularly, macrocycles that possess five or fewer monomer units constituting the macrocycle. Methods to retain the stable conformation of individual sugar units on small-ring macrocyles and the benefits to supramolecular properties are discussed. © 2020 Arkat. All rights reserved.

Item Type: Journal Article
Publication: Arkivoc
Publisher: Arkat
Additional Information: The copyright for this article belongs to The Authors.
Keywords: Cyclic oligosaccharides; Cyclo-oligomerization; Cyclodextrins; Glycosylation; Small-ring macrocycles
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 11 Jan 2023 05:03
Last Modified: 11 Jan 2023 05:03
URI: https://eprints.iisc.ac.in/id/eprint/79036

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