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A Maskless Process for Fabrication of Patterned Surfaces with Microscale Superhydrophobic Borders for High Throughput Droplet Microarray Printing

Khuushi, K and Srinivasan, SK and Modak, CD and Kumar, A and Tripathy, A and Sen, P (2019) A Maskless Process for Fabrication of Patterned Surfaces with Microscale Superhydrophobic Borders for High Throughput Droplet Microarray Printing. In: 32nd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2019, 27 - 31 January 2019, Seoul, pp. 389-391.

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Official URL: https://doi.org/10.1109/MEMSYS.2019.8870702

Abstract

We demonstrate a novel and simple fabrication technique to create a 2D array of liquid capturing micro-regions separated by superhydrophobic borders on polydimethylsiloxane (PDMS). The pattern with microscale superhydrophobic borders was formed by transfer of nanostructures grown on a copper mesh. Our technique does not require the use of any sophisticated equipment, thus making it simple, cost-effective and easily scalable. The capturing regions defined by the superhydrophobic borders can trap droplets having volume as low as 2.1 picolitres (pL) when exposed to a liquid. Trapped droplet volume depends on the dimension of the liquid capture region, which is determined by the pore opening (L) of the copper mesh. We demonstrate capture of various aqueous droplets of different sizes on different surfaces. These surfaces can be used in a variety of applications where cell culture in small volumes is required (e.g. cell differentiation, forming genome libraries etc.).

Item Type: Conference Paper
Publication: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Publisher: Institute of Electrical and Electronics Engineers Inc.
Additional Information: The copyright for this article belongs to Institute of Electrical and Electronics Engineers Inc.
Keywords: Cell culture; Copper; Cost effectiveness; Drops; Fabrication; Hydrophobicity; Liquids; Mesh generation; Polydimethylsiloxane; Silicones, Aqueous droplets; Cell differentiation; Fabrication technique; Genome libraries; Micro-array printing; Patterned surface; Polydimethylsiloxane PDMS; Superhydrophobic, MEMS
Department/Centre: Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited: 06 Dec 2022 05:46
Last Modified: 06 Dec 2022 05:46
URI: https://eprints.iisc.ac.in/id/eprint/78261

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