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Generation of neutral pH high-strength plasma-activated water from a pin to water discharge and its bactericidal activity on multidrug-resistant pathogens

Punith, N and Singh, AK and Ananthanarasimhan, J and Boopathy, B and Chatterjee, R and Hemanth, M and Chakravortty, D and Rao, L (2022) Generation of neutral pH high-strength plasma-activated water from a pin to water discharge and its bactericidal activity on multidrug-resistant pathogens. In: Plasma Processes and Polymers .

Full text not available from this repository.
Official URL: https://doi.org/10.1002/ppap.202200133

Abstract

Plasma-activated water (PAW) is emerging as a green alternative technology in biomedicine due to its rich and diverse aqueous reactive nitrogen and oxygen species (RONS). This study explores how to configure a pin to water (P2W) discharge to generate neutral pH high-strength plasma-activated water (hs-PAW) and its bactericidal activity on hypervirulent multidrug resistance (MDR) pathogens. The factors affecting the strength of PAW, namely: water type, PAW temperature, plasma enclosure, and activation time, were studied and optimized to generate hs-PAW having 650 ± 40 mg/l of (Formula presented.) and 215 ± 15 mg/l of H2O2 at a pH of 7. This study demonstrates a simple P2W discharge set up to handle the MDR pathogens and can be easily scalable for real-world medical applications.

Item Type: Journal Article
Publication: Plasma Processes and Polymers
Publisher: John Wiley and Sons Inc
Additional Information: The copyright for this article belongs to John Wiley and Sons Inc.
Keywords: Bacteria; Bactericides; Electric discharges; Nitrogen plasma, Bactericidal activity; High-strength; High-strength plasma activated water; Hypervirulent klebsiellum pneumonia; Klebsiella pneumoniae; Methicillin-resistant staphylococcus aureus; Multidrug resistance; Neutral pH; Plasma-activated waters; Water discharges, Medical applications
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Division of Mechanical Sciences > Centre for Sustainable Technologies (formerly ASTRA)
Date Deposited: 02 Nov 2022 05:17
Last Modified: 02 Nov 2022 05:17
URI: https://eprints.iisc.ac.in/id/eprint/77670

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