Kotesa, RS and Dutt, T and Sen, P (2018) Overcoming limitations in cell size estimation using electrical impedance spectroscopy. In: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, 11 - 15 November 2018, Kaohsiung, pp. 1339-1341.
Full text not available from this repository.Abstract
We report a novel method to estimate cell size in a microchannel using Electrical Impedance Spectroscopy (EIS) which is independent of flow rate fluctuations, cell z-position and amplitude of the signal. The platform uses two sets of coplanar electrode pair integrated in a microchannel to measure the impedance change during a cell transit. The size of a cell is measured using time information embedded in the electrical signals. We observed the evolution and decay of the electrical signals during a cell transit and compared it with optical measurements. The electrically and optically measured transit time suggests the dependence of the width of electrical signal on the cell size. Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.
| Item Type: | Conference Paper |
|---|---|
| Publication: | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
| Publisher: | Chemical and Biological Microsystems Society |
| Additional Information: | The copyright for this article belongs to Chemical and Biological Microsystems Society |
| Keywords: | Electric impedance; Electric impedance measurement; Microchannels; Optical data processing, Cell size; Co-planar electrodes; Cytometry; Electrical impedance spectroscopy; Electrical signal; Flow rate fluctuations; Optical measurement; Simulation, Spectroscopy |
| Department/Centre: | Division of Biological Sciences > Microbiology & Cell Biology |
| Date Deposited: | 01 Sep 2022 09:25 |
| Last Modified: | 01 Sep 2022 09:25 |
| URI: | https://eprints.iisc.ac.in/id/eprint/75730 |
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