Controlled synthesis of Ag/CuO nanocomposites: evaluation of their antimycobacterial, antioxidant, and anticancer activities

Prashanth, GK and Sathyananda, HM and Prashanth, PA and Gadewar, M and Mutthuraju, M and Prabhu, SRB and Nagabhushana, BM and Shivakumara, C and Rao, S and Mohanty, D (2022) Controlled synthesis of Ag/CuO nanocomposites: evaluation of their antimycobacterial, antioxidant, and anticancer activities. In: Applied Physics A: Materials Science and Processing, 128 (7).

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Abstract

Herein we summarize the production of silver/copper oxide nanocomposites (Ag/CuO NCs) by a facile solution combustion method with the aid of abio-fuel as reductant. Powder XRD results revealed the formation of Ag/CuO NCs with average crystallite size ranging from 20 to 25 nm. These NCs were tested for their antimycobacterial activity against four mycobacterium species namely Mycobacterium tuberculosis H37Rv ATCC 27294, Mycobacterium abscessus ATCC 19977, Mycobacterium fortuitum ATCC 6841, Mycobacterium chelonae ATCC and anticarcinogenic activity on breast cancer cell line MDA-MB-231. Scavenging activity was evaluated by the 2, 2-diphenyl-1-picrylhydrazyl hydrate (DPPH) method. Results indicated that the Ag/CuO NCs had higher anticancer and slightly better scavenging activities than the undoped CuO nanoparticles.

Item Type:	Journal Article
Publication:	Applied Physics A: Materials Science and Processing
Publisher:	Springer Science and Business Media Deutschland GmbH
Additional Information:	The copyright for this article belongs to the Springer Science and Business Media Deutschland GmbH.
Keywords:	Antioxidants; Cell culture; Copper oxides; Crystallite size; Nanoparticles; Synthesis (chemical), Ag/CuO nanocomposite; Anti-mycobacterial; Anticarcinogenic; Antimycobacterial activity; Antioxidant and anticancer activities; Controlled synthesis; CuO nanoparticles; Scavenging activities; Silver-copper oxides; Solution combustion method, Nanocomposites
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	14 Jul 2022 09:53
Last Modified:	14 Jul 2022 09:53
URI:	https://eprints.iisc.ac.in/id/eprint/74416

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