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Role of Vitamin D on cognitive performance among healthy volunteers of SANSCOG cohort

Menesgere, A and Giridhar, V and Bota, R and Ravindranath, V (2022) Role of Vitamin D on cognitive performance among healthy volunteers of SANSCOG cohort. In: Clinical Nutrition Open Science, 44 . pp. 1-8.

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Official URL: https://doi.org/10.1016/j.nutos.2022.05.006


Background and aims: Nutrients such as vitamin D play an important role in aging and dementia and evidence on the effect of vitamin D on cognition among healthy aging adults especially in rural India is sparse. Our aim was to observe the effect of vitamin D on cognition. Methods: Using a cross-sectional study design we examined cognitive performance between vitamin D sufficient, vitamin D insufficient and vitamin D deficient groups among the cognitively healthy volunteers of SANSCOG cohort. Results: Our analysis revealed that two thirds (74.5) had suboptimal vitamin D levels (Insufficiency-38.3 and Deficiency-36.2) and women were more affected than men. Vitamin D levels affected subject's depression scores and diabetes status negatively, however no effect was found on cognitive performance. Discussion: It may be postulated that vitamin D plays an indirect role on cognitive performance. Large proportion of suboptimal vitamin D levels in the rural population warrants proactive public health measures.

Item Type: Journal Article
Publication: Clinical Nutrition Open Science
Publisher: Elsevier B.V.
Additional Information: The copyright for this article belongs to the Elsevier B.V.
Keywords: vitamin D, adult; Article; clinical dementia rating scale; cognitive defect; cohort analysis; controlled study; cross-sectional study; depression; diabetes mellitus; female; human; human experiment; interrater reliability; longitudinal study; male; mental performance; normal human; nutrient intake; observational study; prevalence; prospective study; public health; randomized controlled trial; reliability; rural population; validity; vitamin blood level; vitamin D deficiency; vitamin supplementation; word list recall
Department/Centre: Division of Biological Sciences > Centre for Neuroscience
Date Deposited: 14 Jul 2022 09:38
Last Modified: 14 Jul 2022 09:38
URI: https://eprints.iisc.ac.in/id/eprint/74411

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