Weak interactions involving organic fluorine: a comparative study of the crystal packing in substituted isoquinolines

Choudhury, AR and Urs, UK and Row, Guru TN and Nagarajan, K (2002) Weak interactions involving organic fluorine: a comparative study of the crystal packing in substituted isoquinolines. In: Journal of Molecular Structure, 605 (1). pp. 71-77.

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Abstract

Weak interactions involving fluorine have been analyzed in the structure of 6-methoxy-1,2-diphenyl-1,2,3,4-tetrahydroisoquinoline with fluorine substitution at para-, meta- and ortho- positions, respectively, on the 1-phenyl ring. The packing modes in the crystalline lattice as determined by X-ray diffraction techniques generate motifs via $F\cdot\cdot\cdot {F}$, $C-H\cdot\cdot\cdot{F}$ and $C-F\cdot\cdot\cdot{\pi}$ interactions. The three structures as compared to the parent compound depict conformational changes in the saturated tetrahydroisoquinoline moiety. The salient features of the four structures in terms of weak interactions involving fluorine suggest that organic fluorine does resemble the other halogens.

Item Type:	Journal Article
Publication:	Journal of Molecular Structure
Publisher:	Elsevier
Additional Information:	Copyright of this article belongs to Elsevier.
Keywords:	Weak interactions Crystal engineering;Crystal packing;Molecular conformation
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	02 Jun 2006
Last Modified:	19 Sep 2010 04:28
URI:	http://eprints.iisc.ac.in/id/eprint/7434

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