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Six decades of UHMWPE in reconstructive surgery

Sharma, V and Chowdhury, S and Keshavan, N and Basu, B (2022) Six decades of UHMWPE in reconstructive surgery. In: International Materials Reviews, 67 (6).

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Official URL: https://doi.org/10.1080/09506608.2022.2047419


Ultra-high molecular weight polyethylene (UHMWPE) materials have played a significant role in the field of reconstructive surgery, particularly as acetabular liners/sockets for total hip joint replacement (THR), and tibial inserts for total knee joint replacement (TKR). This review aims to provide a perspective on key elements regarding the processing–structure–property relationship of UHMWPE and derivatives. Much emphasis will be provided to discuss the clinically relevant properties of UHMWPE blend/composite formulation, Vitamin-E reinforced or highly crosslinked variants. In addition, we provide clinical insights into the role of wear debris in inflammation and osteolysis. The relatively unexplored domain of UHMWPE additive manufacturing. Finally, the relatively unexplored domain of UHMWPE additive manufacturing and the opportunities associated with the next generation of UHMWPE implants are highlighted.

Item Type: Journal Article
Publication: International Materials Reviews
Publisher: Taylor and Francis Ltd.
Additional Information: The copyright for this article belongs to Taylor and Francis Ltd.
Keywords: 3D printers; Additives; Arthroplasty; Hip prostheses; Implants (surgical); Joints (anatomy); Knee prostheses; Nonmetallic matrix composites, Acetabular liners; Aseptic loosening; Biological response; Implant failures; Knee joint replacement; Osteolysis; Reconstructive surgery; Tibial inserts; Total hip joint replacements; Total knee joints, Ultrahigh molecular weight polyethylenes
Department/Centre: Division of Chemical Sciences > Materials Research Centre
Date Deposited: 28 Jun 2022 08:59
Last Modified: 29 Jun 2022 10:31
URI: https://eprints.iisc.ac.in/id/eprint/74103

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