Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α-Aminophosphonates

Dhineshkumar, Jayaraman and Samaddar, Prasanjit and Prabhu, Kandikere Ramaiah (2017) Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α-Aminophosphonates. In: ACS Omega, 2 (8). pp. 4885-4893. ISSN 2470-1343

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Abstract

α-Aminophosphonates are synthesized by employing unfunctionalized starting materials using cross-dehydrogenative coupling strategy. This method does not require any catalyst and proceeds in the presence of open air as the only oxidant. Mechanistic studies revealed that the reaction is nucleophile dependent and specific to dialkyl phosphite and N-aryl tetrahydroisoquinoline derivatives.

Item Type:	Journal Article
Publication:	ACS Omega
Publisher:	American Chemical Society
Additional Information:	The Copyright of the article belongs to the Authors.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	06 Jun 2022 05:02
Last Modified:	06 Jun 2022 05:02
URI:	https://eprints.iisc.ac.in/id/eprint/72945

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