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Structural and Functional Characterization of Sesbania Mosaic Virus

Bakshi, Arindam and Vishnu Vardhan, GP and Hema, M and Murthy, MRN and Savithri, HS (2017) Structural and Functional Characterization of Sesbania Mosaic Virus. [Book Chapter]

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Official URL: https://doi.org/10.1007/978-981-10-5672-7_18


The genus Sobemovirus includes isometric, single-stranded positive sense RNA plant viruses that infect monocots and dicots. Sesbania mosaic virus (SeMV) is the only sobemovirus, which has been studied extensively in India. SeMV, which was identified in southern India, is highly stable and multiplies to high concentration causing mosaic symptoms on the leaves of Sesbania grandiflora. SeMV has served as a good model for understanding the molecular mechanism of assembly, replication and movement of sobemoviruses. The structure of the virion and other chimeric VLPs, along with biochemical investigations has resulted in the elucidation of the mechanism of assembly of SeMV. The complete genome sequence, structure and function of non-structural proteins have also been determined. The review presents a summary of all these findings. SeMV being non-toxic and biodegradable and of low immune response, has been shown as a good candidate for biomedical applications.

Item Type: Book Chapter
Publisher: Springer Singapore
Additional Information: The copyright of this article belongs to the Springer Singapore.
Keywords: Infectious clone; Sesbania mosaic virus; Structure of SeMV; Virus-like particle
Department/Centre: Division of Biological Sciences > Biochemistry
Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 26 May 2022 04:52
Last Modified: 26 May 2022 04:52
URI: https://eprints.iisc.ac.in/id/eprint/72656

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