Arora, Gunjan and Kulshreshtha, Ankur and Arora, Kriti and Talwar, Puneet and Raj, Rishi and Grewal, Gurpreet and Sajid, Andaleeb and Kukreti, Ritushree (2017) Emerging Themes in Drug Resistance. [Book Chapter]
Full text not available from this repository.Abstract
In the last century, advances in biomedical sciences led to improvements in quality of human life mainly by decreasing the disease burden and providing various healthcare innovations. Effective medications were developed for most infectious diseases, lifestyle disorders, and other diseases. For once, we all believed that we can create a disease-free world; however, the excessive use of medications generated drug-resistant human pathogens leading to untreatable forms of many diseases. In the last few decades, the focus has been to understand the evolution of drug resistance, tackle the current drug-resistant disease agents, and develop new drugs that are potent and reliable for long-term usage. In this chapter, we will discuss the emerging themes in drug resistance research. As biologists are gaining deeper understanding of cellular complexity and disease agents, numerous modern themes have been pursued. The focus is to identify novel drug targets and develop specific drug molecules detrimental for the disease causing pathogens, and to harness host immunity. For the scope of this chapter, we will primarily discuss pharmacogenomics, therapeutic antibodies, cell-to-cell communication, exosomes, structuromics, and posttranslational modifications.
| Item Type: | Book Chapter |
|---|---|
| Publisher: | Springer International Publishing |
| Additional Information: | The Copyright of this article belongs to the Springer |
| Keywords: | Respiratory Syncytial Virus; Extracellular Vesicle; Therapeutic Antibody; Buruli Ulcer; SLCO1B1 Gene |
| Department/Centre: | Division of Biological Sciences > Molecular Biophysics Unit |
| Date Deposited: | 29 May 2022 05:02 |
| Last Modified: | 31 May 2022 04:55 |
| URI: | https://eprints.iisc.ac.in/id/eprint/72574 |
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