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Curcumin-Artemisinin Combination Therapy for Malaria

Nandakumar, Dalavaikodihalli Nanjaiah and Nagaraj, Viswanathan Arun and Vathsala, Palakkod Govindan and Rangarajan, Pundi and Padmanaban, Govindarajan (2006) Curcumin-Artemisinin Combination Therapy for Malaria. In: Antimicrobial Agents and Chemotherapy, 50 (5). pp. 1859-1860.

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Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of ${\alpha}{\beta}$-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to ${\alpha}{\beta}$-arteether monotherapy and ensure almost 100% survival of the animals.

Item Type: Journal Article
Publication: Antimicrobial Agents and Chemotherapy
Publisher: American Society for Microbiology
Additional Information: Copyright of this article belongs to American Society for Microbiology.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 30 May 2006
Last Modified: 27 Aug 2008 12:05
URI: http://eprints.iisc.ac.in/id/eprint/7120

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