ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Simplifying Molecular Transport in Polyelectrolyte Multilayer Thin Films

Pahal, S and Boranna, R and Prashanth, GR and Varma, MM (2022) Simplifying Molecular Transport in Polyelectrolyte Multilayer Thin Films. In: Macromolecular Chemistry and Physics, 223 (1).

[img] PDF
mac_che_phy_223_2022.pdf - Published Version
Restricted to Registered users only

Download (2MB) | Request a copy
Official URL: https://doi.org/10.1002/macp.202100330


The matrix properties of polyelectrolyte multilayer thin films (PEM) are critical in making them a viable candidate for various biomedical applications. The location and ability of molecules to diffuse through the PEM architecture determines their encapsulation and release capabilities in a given matrix for various biomedical applications. The main aim of this review article is to provide a complete understanding of molecular transport on the surface as well as across the bulk of the PEM matrix. Different physiochemical strategies to promote or suppress the diffusivity of various molecules inside the PEM are mentioned in brief. A set of guiding principles is uncovered for getting a complete picture of loading and release of molecules across the PEM structure, which can play a key role in designing a desirable PEM assembly and have important implications for designing multicomponent, targeted and controlled drug-delivery vehicles. Understanding the molecular diffusivity in PEM stack at the nano and micro scales will help to design superior host materials for biomedical engineering applications.

Item Type: Journal Article
Publication: Macromolecular Chemistry and Physics
Publisher: John Wiley and Sons Inc
Additional Information: The copyright for this article belongs to the John Wiley and Sons Inc.
Keywords: Biomedical engineering; Controlled drug delivery; Film preparation; Molecules; Multilayer films; Multilayers; Polyelectrolytes; Targeted drug delivery, Biomedical applications; Guiding principles; Layer-by-layer assemblies; matrix; Molecular transport; Multi-layer thin film; Multicomponents; Physio-chemical; Polyelectrolyte multilayer; Property, Medical applications
Department/Centre: Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited: 13 Dec 2021 11:40
Last Modified: 08 Jul 2022 05:17
URI: https://eprints.iisc.ac.in/id/eprint/70772

Actions (login required)

View Item View Item