Aryne Three-Component Coupling Involving CS2for the Synthesis of S-Aryl Dithiocarbamates

Bhattacharjee, S and Deswal, S and Manoj, N and Jindal, G and Biju, AT (2021) Aryne Three-Component Coupling Involving CS2for the Synthesis of S-Aryl Dithiocarbamates. In: Organic Letters .

	PDF org_let_2021.pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy
	PDF ol1c03378_si_001.pdf - Published Supplemental Material Restricted to Registered users only Download (6MB) | Request a copy

Abstract

A facile synthesis of biologically important S-aryl dithiocarbamates has been demonstrated by the aryne three-component coupling involving CS2 and aliphatic amines. This transition-metal-free and mild reaction is scalable and operates with good functional group compatibility. Preliminary mechanistic experiments, including density functional theory studies, are also provided. Moreover, with 3-triflyloxybenzynes, a unique four-component coupling incorporating tetrahydrofuran was observed. © 2021 American Chemical Society.

Item Type:	Journal Article
Publication:	Organic Letters
Publisher:	American Chemical Society
Additional Information:	The copyright for this article belongs to American Chemical Society
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	13 Dec 2021 11:35
Last Modified:	13 Dec 2021 11:35
URI:	http://eprints.iisc.ac.in/id/eprint/70752

Actions (login required)

View Item