Electrochemical sensors for the detection of SARS-CoV-2 virus

Kumar, N and Shetti, NP and Jagannath, S and Aminabhavi, TM (2022) Electrochemical sensors for the detection of SARS-CoV-2 virus. In: Chemical Engineering Journal, 430 .

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Abstract

Coronavirus (COVID-19), a deadly pandemic has spread worldwide and created many global health issues. Though methods of its detection are being continuously developed for the early detection and monitoring of COVID-19, still there is need for more novel methods. The presently used methods include rapid antigen tests, serological surveys, reverse transcription-polymerase chain reaction (RT-PCR), artificial intelligence-based techniques, and assays based on sensors/biosensors. Of all these, RT-PCR test has high sensitivity and specificity though it requires more time for testing and need for skilled technicians. Recently, electrochemical sensors have been developed for rapid monitoring and detection of SARS-CoV-2 from the patient's biological fluid samples. This review covers the recently developed electrochemical sensors that are focused on the detection of viral nucleic acid, immunoglobulin, antigen, and the entire viral particles. In addition, we also compare and assess their detection limits, sensitivities and specificities for the identification and monitoring of COVID-19. Furthermore, this review will address the best practices for the development of electrochemical sensors such as electrode fouling, limit of detection/limit of quantification determination and verification. © 2021

Item Type:	Journal Article
Publication:	Chemical Engineering Journal
Publisher:	Elsevier B.V.
Additional Information:	The copyright for this article belongs to Authors
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	28 Nov 2021 09:39
Last Modified:	28 Nov 2021 09:39
URI:	http://eprints.iisc.ac.in/id/eprint/70400

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