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Four-Step Total Synthesis of (+)-Euphococcinine and (±)-Adaline

Khandare, SP and Prasad, KR (2021) Four-Step Total Synthesis of (+)-Euphococcinine and (±)-Adaline. In: Journal of Organic Chemistry .

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Official URL: https://doi.org/10.1021/acs.joc.1c00938


A four-step enantiospecific total synthesis of bicyclic homotropinone alkaloid euphococcinine and a racemic synthesis of adaline were reported. Key reactions in the synthesis are the diastereoselective addition of a Wittig phosphorene to the ketimines derived from Davis-Ellman sulfinamides, ring-closing metathesis, and intramolecular Michael reactions. ©

Item Type: Journal Article
Publication: Journal of Organic Chemistry
Publisher: American Chemical Society
Additional Information: The copyright for this article belongs to American Chemical Society
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 03 Dec 2021 07:51
Last Modified: 03 Dec 2021 07:51
URI: http://eprints.iisc.ac.in/id/eprint/70164

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