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Active suppression of leaflet emergence as a mechanism of simple leaf development

Challa, KR and Rath, M and Sharma, AN and Bajpai, AK and Davuluri, S and Acharya, KK and Nath, U (2021) Active suppression of leaflet emergence as a mechanism of simple leaf development. In: Nature Plants .

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Official URL: https://doi.org/10.1038/s41477-021-00965-3


Angiosperm leaves show extensive shape diversity and are broadly divided into two forms; simple leaves with intact lamina and compound leaves with lamina dissected into leaflets. The mechanistic basis of margin dissection and leaflet initiation has been inferred primarily by analysing compound-leaf architecture, and thus whether the intact lamina of simple leaves has the potential to initiate leaflets upon endogenous gene inactivation remains unclear. Here, we show that the CINCINNATA-like TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORS (CIN-TCP) transcription factors activate the class II KNOTTED1-LIKE (KNOX-II) genes and the CIN-TCP and KNOX-II proteins together redundantly suppress leaflet initiation in simple leaves. Simultaneous downregulation of CIN-TCP and KNOX-II in Arabidopsis leads to the reactivation of the stemness genes KNOX-I and CUPSHAPED COTYLEDON (CUC) and triggers ectopic organogenesis, eventually converting the simple lamina to a super-compound form that appears to initiate leaflets indefinitely. Thus, a conserved developmental mechanism promotes simple leaf architecture in which CIN-TCP�KNOX-II forms a strong differentiation module that suppresses the KNOX-I-CUC network and leaflet initiation. © 2021, The Author(s), under exclusive licence to Springer Nature Limited.

Item Type: Journal Article
Publication: Nature Plants
Publisher: Nature Research
Additional Information: The copyright for this article belongs to Nature Research
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 28 Nov 2021 09:48
Last Modified: 28 Nov 2021 09:48
URI: http://eprints.iisc.ac.in/id/eprint/69981

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