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Recent technical advances in whole slide imaging instrumentation

Katare, P and Gorthi, SS (2021) Recent technical advances in whole slide imaging instrumentation. In: Journal of Microscopy .

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Official URL: https://doi.org/10.1111/jmi.13049


Microscopic observation of biological specimen smears is the mainstay of diagnostic pathology, as defined by the Digital Pathology Association. Though automated systems for this are commercially available, their bulky size and high cost renders them unusable for remote areas. The research community is investing much effort towards building equivalent but portable, low-cost systems. An overview of such research is presented here, including a comparative analysis of recent reports. This paper also reviews recently reported systems for automated staining and smear formation, including microfluidic devices; and optical and computational automated microscopy systems including smartphone-based devices. Image pre-processing and analysis methods for automated diagnosis are also briefly discussed. It concludes with a set of foreseeable research directions that could lead to affordable, integrated and accurate whole slide imaging systems. © 2021 Royal Microscopical Society

Item Type: Journal Article
Publication: Journal of Microscopy
Publisher: John Wiley and Sons Inc
Additional Information: The copyright for this article belongs to John Wiley and Sons Inc
Department/Centre: Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics
Date Deposited: 21 Nov 2021 16:29
Last Modified: 21 Nov 2021 16:29
URI: http://eprints.iisc.ac.in/id/eprint/69944

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