Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate

Harisha, MB and Dhanalakshmi, P and Suresh, R and Kumar, RR and Muthusubramanian, S (2020) Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate. In: Beilstein Journal of Organic Chemistry, 16 . pp. 2108-2118.

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Abstract

The reactivity of α-azidochalcones has been explored for the preparation of highly substituted oxazoles via a 2H-azirine intermediate. The azidochalcones, when treated with potassium thiocyanate in the presence of potassium persulfate, lead to 2,4,5-trisubstituted oxazoles in good yields. Incidentally, 2-aminothiazoles are the products when ferric nitrate is employed instead of persulfate in the above reaction. © 2020 Harisha et al.

Item Type:	Journal Article
Publication:	Beilstein Journal of Organic Chemistry
Publisher:	Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
Additional Information:	The copyright of this article belongs to Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	24 Feb 2021 06:20
Last Modified:	24 Feb 2021 06:20
URI:	http://eprints.iisc.ac.in/id/eprint/68047

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