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Bioinorganic chemistry research in India

Mugesh, G (2020) Bioinorganic chemistry research in India. In: Proceedings of the Indian National Science Academy, 86 (2). pp. 929-936.

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Official URL: https://dx.doi.org/10.16943/ptinsa/2019/49729


Nature uses metal ions and metal containing biomolecules for carrying out crucial cellular processes. They are mostly associated with the protein core, or found in cofactors such as porphyrins, or in protein-bound clusters. A few processes and reaction which involve the metals are respiration, photosynthesis, complex DNA synthesis and repair mechanisms, circulation, muscle contraction, etc. Bioinorganic chemistry deals with the study of metal ions and their importance in biological system. This article encompasses the progress and current status in the understanding of metalloenzymes and biomimetic inorganic chemistry, especially in India. The broad aspects of metals in medicine; use of metal containing nanoparticles and complexes for therapeutic and diagnostic purposes; the array of methodologies employed to understand and mimic the structure and function of metallobiomolecules; metal containing compounds in bioremediation etc. are discussed. Further, the significance and a future prospect of the bioinorganic chemistry research are elucidated briefly. © 2020 Indian National Science Academy. All rights reserved.

Item Type: Journal Article
Publication: Proceedings of the Indian National Science Academy
Publisher: Indian National Science Academy
Additional Information: Copyright to this article belongs to Indian National Science Academy
Keywords: Biochemistry; Biomimetics; Biomolecules; Bioremediation; Diagnosis; Inorganic compounds; Metal ions; Metal nanoparticles; Muscle; Proteins, Bioinorganic chemistry; Cellular process; Future prospects; Inorganic chemistry; Metal-containing nanoparticles; Metalloenzymes; Muscle contractions; Repair mechanism, Metals
Department/Centre: Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited: 21 Jan 2021 07:09
Last Modified: 21 Jan 2021 07:09
URI: http://eprints.iisc.ac.in/id/eprint/67739

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