ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

A transport-reaction model for expanding the dynamic range of lateral flow immunoassays using real-time imaging

Sathishkumar, N and Toley, BJ (2019) A transport-reaction model for expanding the dynamic range of lateral flow immunoassays using real-time imaging. In: 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, 27-31 October 2019, Basel; Switzerland, pp. 1020-1021.

Full text not available from this repository.

Abstract

This study presents the first transport-reaction model that successfully captures the real-time response of test and control line intensities in lateral flow immunoassays (LFIA's) and the expansion of dynamic range by monitoring real-time signal generation. We also present experimental results of mitigating the hook effect in commercially available pregnancy strips using real time imaging and demonstrate strong agreement between the predictions of our model and experiments results. These results show potential to expand the dynamic range of LFIA's up to two orders of magnitude. © 2019 CBMS-0001.

Item Type: Conference Paper
Publication: 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Publisher: Chemical and Biological Microsystems Society
Additional Information: The copyright of this article belongs to Chemical and Biological Microsystems Society
Department/Centre: Division of Mechanical Sciences > Chemical Engineering
Date Deposited: 12 Mar 2021 16:12
Last Modified: 12 Mar 2021 16:13
URI: http://eprints.iisc.ac.in/id/eprint/67502

Actions (login required)

View Item View Item