Chemical reactivity of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones towards nitrogen nucleophiles. Part 1. One-pot ring conversion of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones into 4-amino-2-aryl-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3

Kavali, Jyothi R and Kotresh, O and Badami, Bharati V (2003) Chemical reactivity of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones towards nitrogen nucleophiles. Part 1. One-pot ring conversion of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones into 4-amino-2-aryl-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3. In: Journal of Chemical Research, 2003 (5). pp. 275-278.

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Abstract

The ring transformation of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones 1a-n into 4-amino-2-aryl-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-ones 3a-n, by reaction with hydrazine hydrate, is described. The products were screened for biological activity, and were found to be active against fungal strains.

Item Type:	Journal Article
Publication:	Journal of Chemical Research
Publisher:	Science Reviews
Additional Information:	The Copyright belongs to Science Reviews.
Keywords:	3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones;nitrogen nucleophiles
Department/Centre:	Division of Chemical Sciences
Date Deposited:	06 May 2006
Last Modified:	19 Sep 2010 04:26
URI:	http://eprints.iisc.ac.in/id/eprint/6626

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