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World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Kivipelto, M and Mangialasche, F and Snyder, HM and Allegri, R and Andrieu, S and Arai, H and Baker, L and Belleville, S and Brodaty, H and Brucki, SM and Calandri, I and Caramelli, P and Chen, C and Chertkow, H and Chew, E and Choi, SH and Chowdhary, N and Crivelli, L and Torre, RDL and Du, Y and Dua, T and Espeland, M and Feldman, HH and Hartmanis, M and Hartmann, T and Heffernan, M and Henry, CJ and Hong, CH and Håkansson, K and Iwatsubo, T and Jeong, J.H and Jimenez-Maggiora, G and Koo, EH and Launer, LJ and Lehtisalo, J and Lopera, F and Martínez-Lage, P and Martins, R and Middleton, L and Molinuevo, JL and Montero-Odasso, M and Moon, SY and Morales-Pérez, K and Nitrini, R and Nygaard, HB and Park, YK and Peltonen, M and Qiu, C and Quiroz, YT and Raman, R and Rao, N and Ravindranath, V and Rosenberg, A and Sakurai, T and Salinas, RM and Scheltens, P and Sevlever, G and Soininen, H and Sosa, A.L and Suemoto, CK and Tainta-Cuezva, M and Velilla, L and Wang, Y and Whitmer, R and Xu, X and Bain, LJ and Solomon, A and Ngandu, T and Carrillo, MC (2020) World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. In: Alzheimer's and Dementia, 16 (7). pp. 1078-1094.

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Official URL: https://doi.org/10.1002/alz.12123


Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk reduction and prevention. WW-FINGERS aims to adapt, test, and optimize the FINGER model to reduce risk across the spectrum of cognitive decline�from at-risk asymptomatic states to early symptomatic stages�in different geographical, cultural, and economic settings. WW-FINGERS aims to harmonize and adapt multidomain interventions across various countries and settings, to facilitate data sharing and analysis across studies, and to promote international joint initiatives to identify globally implementable and effective preventive strategies. © 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association

Item Type: Journal Article
Publication: Alzheimer's and Dementia
Publisher: John Wiley and Sons Inc.
Additional Information: Copy right for this article belongs to John Wiley and Sons Inc.
Keywords: Alzheimer’s disease, cognitive impairment, dementia, lifestyle, multidomain intervention, prevention, randomized controlled trial,World-Wide FINGERS
Department/Centre: Autonomous Societies / Centres > Centre for Brain Research
Date Deposited: 04 Dec 2020 05:22
Last Modified: 04 Dec 2020 05:22
URI: http://eprints.iisc.ac.in/id/eprint/66068

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