Plasma-activated water from a dielectric barrier discharge plasma source for the selective treatment of cancer cells

Subramanian, PSG and Jain, A and Shivapuji, AM and Sundaresan, NR and Dasappa, S and Rao, L (2020) Plasma-activated water from a dielectric barrier discharge plasma source for the selective treatment of cancer cells. In: Plasma Processes and Polymers, 17 (8).

	PDF pla_pro_pol_17_8.pdf - Published Version Restricted to Registered users only Download (2MB) | Request a copy
	Microsoft Word supplementary_material (Plasma-activated).docx - Published Version Restricted to Registered users only Download (15kB) | Request a copy

Abstract

In this study, cold plasma was used to prepare plasma-activated water (PAW) from a dielectric barrier discharge plasma source, with ambient air as the plasma-forming gas. The PAW prepared was characterized for its physicochemical parameters, some of which followed a strong linear correlation with activation time (ta). The effects of PAW addition on the cell viability of human breast cancer cells (MDA-MB-231) and healthy murine muscle-derived fibroblast cells were investigated using the MTT assay. The volume of PAW added and ta of PAW showed a significant impact. The PAW prepared was selective toward killing cancer cells at specific ta. PAW retains its potency against cancer cells after 14 days of refrigerated storage. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Item Type:	Journal Article
Publication:	Plasma Processes and Polymers
Publisher:	Wiley-VCH Verlag
Additional Information:	copyright of this article belongs to Wiley-VCH Verlag
Keywords:	activation time, cancer cells, cold plasma, dielectric barrier, discharge plasma‐activated water
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology Division of Interdisciplinary Sciences > Centre for Biosystems Science and Engineering Division of Mechanical Sciences > Centre for Sustainable Technologies (formerly ASTRA)
Date Deposited:	12 Oct 2020 10:26
Last Modified:	12 Oct 2020 10:26
URI:	http://eprints.iisc.ac.in/id/eprint/65434

Actions (login required)

View Item