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Optical spectroscopy-based imaging techniques for the diagnosis of breast cancer: A novel approach

Pal, UM and Saxena, M and Anil Vishnu, GK and Parsana, D and Sarvani, BSR and Varma, M and Jayachandra, M and Kurpad, V and Baruah, D and Gogoi, G and Vaidya, JS and Pandya, HJ (2020) Optical spectroscopy-based imaging techniques for the diagnosis of breast cancer: A novel approach. In: Applied Spectroscopy Reviews .

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Official URL: https://dx.doi.org/ 0.1080/05704928.2020.1749651


There have been substantial advancements in optical spectroscopy-based imaging techniques in recent years. These developments can potentially herald a transformational change in the diagnostic pathway for diseases such as cancer. In this paper, we review the clinical and engineering aspects of novel optical spectroscopy-based imaging tools. We provide a comprehensive analysis of optical and non-optical spectroscopy-based breast cancer diagnosis techniques vis-Ã -vis the current standard techniques such as X-Ray mammography, ultrasonography, and tissue biopsy. The recent advancements in optical spectroscopy-based imaging systems such as Transillumination Imaging (TI) and the various types of Diffuse Optical Imaging (DOI) systems (parallel-plate, bed-based, and handheld) are examined. The engineering aspects, including mechanical, electronics, optics, automatic interpretation using artificial intelligence (AI), and ergonomics are discussed. The abilities of these technologies for measuring several cancer biomarkers such as hemoglobin, water, lipid, collagen, oxygen saturation (SO2), and tissue oxygenation index (TOI) are investigated. This article critically assesses the diagnostic ability and practical deployment of these new technologies to differentiate between the normal and cancerous tissue.

Item Type: Journal Article
Publication: Applied Spectroscopy Reviews
Additional Information: The copyright of this article belongs to TAYLOR & FRANCIS INC
Keywords: Diagnosis; Diseases; Ergonomics; Hemoglobin oxygen saturation; Light; Spectroscopy; Tissue, Breast cancer diagnosis; Comprehensive analysis; Diagnostic ability; Diffuse optical imaging (DOI); Engineering aspects; Optical spectroscopy; Tissue oxygenation index; X-ray mammography, Medical imaging
Department/Centre: Division of Electrical Sciences > Electronic Systems Engineering (Formerly Centre for Electronic Design & Technology)
Division of Interdisciplinary Sciences > Centre for Biosystems Science and Engineering
Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited: 22 Jun 2020 09:56
Last Modified: 22 Jun 2020 09:56
URI: http://eprints.iisc.ac.in/id/eprint/65314

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