IMRPS: Inserted and Modified Residues in Protein Structures. A database

Santhosh, R and Bankoti, N and Gurudarshan, M and Jeyakanthan, J and Sekar, K (2020) IMRPS: Inserted and Modified Residues in Protein Structures. A database. In: Journal of Applied Crystallography, 53 . pp. 569-573.

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Abstract

Modified residues present in proteins are the result of post-translational modifications (PTMs). These PTMs increase the functional diversity of the proteome and influence various biological processes and diseased conditions. Therefore, identification and understanding of PTMs in various protein structures is of great significance. In view of this, an online database, Inserted and Modified Residues in Protein Structures (IMRPS), has been developed. IMRPS is a derived database that furnishes information on the residues modified and inserted in the protein structures available in the Protein Data Bank (PDB). The database is equipped with a graphical user interface and has an option to view the data for non-redundant protein structures (25 and 90) as well. A quality criteria cutoff has been incorporated to assist in displaying the specific set of PDB codes. The entire protein structure along with the inserted or modified residues can be visualized in JSmol. This database will be updated regularly (presently, every three months) and can be accessed through the URL http://cluster.physics.iisc.ac.in/imrps/. © 2020.

Item Type:	Journal Article
Publication:	Journal of Applied Crystallography
Publisher:	International Union of Crystallography
Additional Information:	The copyright for this article belongs to International Union of Crystallography
Keywords:	Database systems; Graphical user interfaces, Biological process; Functional diversity; Non-redundant; Online database; Post-translational modifications; Protein data bank; Protein structures; Quality criteria, Proteins
Department/Centre:	Division of Interdisciplinary Sciences > Computational and Data Sciences
Date Deposited:	11 Aug 2021 09:59
Last Modified:	11 Aug 2021 09:59
URI:	http://eprints.iisc.ac.in/id/eprint/65225

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