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Sulfoxonium-Ylide-Directed C-H Activation and Tandem (4 + 1) Annulation

Hanchate, V and Devarajappa, R and Prabhu, KR (2020) Sulfoxonium-Ylide-Directed C-H Activation and Tandem (4 + 1) Annulation. In: Organic Letters .

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Official URL: https://doi.org/10.1021/acs.orglett.0c00451


Rh(III)-catalyzed C-H activation and cyclization of sulfoxonium ylide with acrylates leads to an efficient synthesis of indanone derivatives. The reaction proceeds under mild and external metal-oxidant-free conditions. The sulfoxonium ylide acts as a traceless directing group as well as an internal oxidant. (4 + 1) Annulation after C-H activation leads to the formation of a carbocyclic ring, and the byproduct obtained is DMSO, which can be easily separated. Copyright © 2020 American Chemical Society.

Item Type: Journal Article
Publication: Organic Letters
Additional Information: The copyright for this article belongs to American Chemical Society
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 03 Nov 2021 09:25
Last Modified: 03 Nov 2021 09:25
URI: http://eprints.iisc.ac.in/id/eprint/65183

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