Aspects of chemical transglycosylations in modern glycoside synthesis

Das, A and Jayaraman, N (2020) Aspects of chemical transglycosylations in modern glycoside synthesis. In: Journal of the Indian Chemical Society, 97 (2). pp. 135-156.

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Abstract

Application of chemical methods forms as a powerful approach to achieve synthesis of custom-designed oligosaccharides. Chemical glycosylation methods continue to evolve till date even when the first such method dates back more than a century ago. The recent past has witnessed the emergence of the transglycosylations, wherein a preponderant O-glycoside acts as a glycosyl donor to afford yet another O-glycoside product bearing the newly introduced glycan/aglycan at the reducing end. Critical requirements of the aglycan portion of a glycoside donor are discussed, as also the mechanistic formulations based on a set of experimental observations. A critical review of the expanding facets of transglycosylations in the garb of modern glycosylation methods is presented herein. © 2020 Scientific Publishers. All rights reserved.

Item Type:	Journal Article
Publication:	Journal of the Indian Chemical Society
Publisher:	Scientific Publishers
Additional Information:	The Copyright of this article belongs to Scientific Publishers
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	23 Aug 2021 09:06
Last Modified:	23 Aug 2021 09:06
URI:	http://eprints.iisc.ac.in/id/eprint/64971

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