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Engineered nanosponges as versatile biodegradable carriers: An insight

Jain, A and Prajapati, SK and Kumari, A and Mody, N and Bajpai, M (2020) Engineered nanosponges as versatile biodegradable carriers: An insight. In: Journal of Drug Delivery Science and Technology, 57 .

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Official URL: https://dx.doi.org/10.1016/j.jddst.2020.101643


Nanotechnology-based advances in nanosponges have impacted the field of drug delivery of biomacromolecules to maximize therapeutic efficacy along with minimizing its untoward effects. Several approaches have been exploited not only to develop nanosponges for targeted and controlled drug delivery but also for photothermal therapy, blood purification, and solubility enhancement. Nanosponges have emerged as a tool of nanotechnology in the field of drug delivery. In order to achieve specific targeted delivery, these tiny sponges can circulate within the body until they encounter its target site to release the drug in a controlled and programmed manner. Recently, various software-based approaches have also been used for the optimization of nanosponges. There are several applications of nanosponges such as increased bioavailability, stability, reduced irritancy and many more. This review attempts to elaborate on merits and demerits, methods of preparation, characterization, optimization approaches, applications, and recent advances in nanosponges.

Item Type: Journal Article
Publication: Journal of Drug Delivery Science and Technology
Publisher: ELSEVIER
Additional Information: The copyright of this article belongs to ELSEVIER
Department/Centre: Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy)
Date Deposited: 26 Jun 2020 07:46
Last Modified: 26 Jun 2020 07:46
URI: http://eprints.iisc.ac.in/id/eprint/64853

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