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Futuristic medical implants using bioresorbable materials and devices

Chatterjee, Suman and Saxena, Mansi and Padmanabhan, Deepak and Jayachandra, Mahesh and Pandya, Hardik J (2019) Futuristic medical implants using bioresorbable materials and devices. In: BIOSENSORS & BIOELECTRONICS, 142 .

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Official URL: https://dx.doi.org/10.1016/j.bios.2019.111489


Implantable medical devices have been used for real-time monitoring of physical parameters (temperature, pressure and biopotentials), sustained drug release, cardiovascular and pulmonary stents and other clinical applications. Several biocompatible materials (titanium and its alloys, aluminium, cobalt-alloys, stainless steel, poly-ethylene, polyurethanes, polyglycolide and polylactides) have been commercially used for fabricating implantable devices. However, these devices require retrieval operations after a certain period. Bioresorbable materials disintegrate gradually in vivo and their derivatives get absorbed completely in the body fluid with no residue and with minimal toxic effects, thus, eliminating the need for retrieval operations. In this article, state-ofthe-art advances in materials, fabrication techniques and clinical applications of bioresorbable implantable devices are reviewed. We first discuss the bioresorbable materials (e.g., magnesium, molybdenum, tungsten, silicon, germanium, silicon dioxide, silicon nitride, silk and synthetic polymers) used in the fabrication of implantable devices. Later, an overview of processes to fabricate pressure, temperature, electrical and chemical sensors are discussed, followed by their applications as implantable devices in biomedical engineering.

Item Type: Journal Article
Additional Information: The copyright for this article belongs to ELSEVIER ADVANCED TECHNOLOGY
Keywords: Bioresorbable materials; Sensor fabrication; Bioresorbable devices; Implantable devices; Clinical applications
Department/Centre: Division of Electrical Sciences > Electronic Systems Engineering (Formerly Centre for Electronic Design & Technology)
Division of Interdisciplinary Sciences > Centre for Biosystems Science and Engineering
Date Deposited: 24 Oct 2019 06:31
Last Modified: 24 Oct 2019 06:31
URI: http://eprints.iisc.ac.in/id/eprint/63762

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