CeVO4 Nanozymes Catalyze the Reduction of Dioxygen to Water without Releasing Partially Reduced Oxygen Species

Singh, Namrata and Mugesh, Govindasamy (2019) CeVO4 Nanozymes Catalyze the Reduction of Dioxygen to Water without Releasing Partially Reduced Oxygen Species. In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58 (23). pp. 7797-7801.

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Abstract

In this study, we report a remarkably active CeVO4 nanozyme that functionally mimics cytochromec oxidase (CcO), the terminal enzyme in the respiratory electron transport chain, by catalyzing a four-electron reduction of dioxygen to water. The nanozyme catalyzes the reaction by using cytochromec (Cyt c), the biological electron donor for CcO, at physiologically relevant pH. The CcO activity of the CeVO4 nanozymes depends on the relative ratio of surface Ce3+/Ce4+ ions, the presence of V5+ and the surface-Cytc interactions. The complete reduction of oxygen to water takes place without release of any partially reduced oxygen species (PROS) such as superoxide, peroxide and hydroxyl radicals.

Item Type:	Journal Article
Publication:	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Publisher:	WILEY-V C H VERLAG GMBH
Additional Information:	copyright for this article belongs to WILEY-V C H VERLAG GMBH
Keywords:	cytochromec oxidase; dioxygen reduction; nanozymes; oxidative stress; superoxide dismutase
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	29 Aug 2019 06:05
Last Modified:	29 Aug 2019 06:05
URI:	http://eprints.iisc.ac.in/id/eprint/63328

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