Rh(III)-Catalyzed Distal C-H Alkenylation of Weakly Coordinating Acetamides Via Desilylation Pathway

Ramesh, Vinay Bapu and Muniraj, Nachimuthu and Prabhu, Kandikere Ramaiah (2019) Rh(III)-Catalyzed Distal C-H Alkenylation of Weakly Coordinating Acetamides Via Desilylation Pathway. In: ADVANCED SYNTHESIS & CATALYSIS, 361 (16). pp. 3683-3688.

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Abstract

Rh(III)-Catalyzed distal ortho-C-H alkenylation of arylacetamides have been reported employing acetamide, a weak coordinating group, as a directing group. This challenging C-H alkenylation of arylacetamides has been achieved by using arylalkynyl silanes as a surrogate for terminal alkynes under redox neutral process through desilylation pathway. The control experiments suggest that the in situ generatedRh-species is likely to be Lewis acidic, which is playing a vital role in the desilylation step.

Item Type:	Journal Article
Publication:	ADVANCED SYNTHESIS & CATALYSIS
Publisher:	WILEY-V C H VERLAG GMBH
Additional Information:	Copyright to this article belongs to WILEY-V C H VERLAG
Keywords:	CATALYZED HYDROARYLATION; TERMINAL ALKYNES; ACTIVATION; BOND; AMIDES; ACIDS; PHENYLACETAMIDES; OLEFINATION; ANNULATION; ACCESS
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	08 Nov 2019 09:41
Last Modified:	08 Nov 2019 09:41
URI:	http://eprints.iisc.ac.in/id/eprint/63257

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