Paul, Apurba and Ramdani, Ghania and Tatu, Utpal and Langsley, Gordon and Natarajan, Vasant (2019) Studying the rigidity of red blood cells induced by Plasmodium falciparum infection. In: SCIENTIFIC REPORTS, 9 .
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Abstract
We study the effect of different chemical moieties on the rigidity of red blood cells (RBCs) induced by Plasmodium falciparum infection, and the bystander effect previously found. The infected cells are obtained from a culture of parasite-infected RBCs grown in the laboratory. The rigidity of RBCs is measured by looking at the Brownian fluctuations of individual cells in an optical-tweezers trap. The results point towards increased intracellular cyclic adenosine monophosphate (cAMP) levels as being responsible for the increase in rigidity.
| Item Type: | Journal Article |
|---|---|
| Publication: | SCIENTIFIC REPORTS |
| Publisher: | NATURE PUBLISHING GROUP |
| Additional Information: | The copyright for this article belongs to the authors |
| Department/Centre: | Division of Biological Sciences > Biochemistry Division of Physical & Mathematical Sciences > Physics |
| Date Deposited: | 16 May 2019 11:52 |
| Last Modified: | 16 May 2019 11:52 |
| URI: | http://eprints.iisc.ac.in/id/eprint/62659 |
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