Spark plasma sintered HA-ZnO ultrafine composite: Mechanical, bactericidal, and cytocompatibility properties

Bajpai, Indu and Basu, Bikramjit (2018) Spark plasma sintered HA-ZnO ultrafine composite: Mechanical, bactericidal, and cytocompatibility properties. In: INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, 15 (4, SI). pp. 961-969.

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Abstract

Calcium-phosphate based hydroxyapatite (HA) biomaterials are widely being investigated due to their osseointegration property, but those inherently lack antibacterial property. In the present work, wet-chemically synthesized rod-shaped zinc oxide (ZnO) is embedded in HA and its role as antibacterial agent without compromising cytocompatability property is established. In particular, HA-xZnO (x=0, 5, 10 wt.%) composites were consolidated by spark plasma sintering at 950 degrees C in vacuum. A host of the spectroscopy and microscopy techniques were utilized to analyze the nature of distribution of ZnO as well as surface chemical characteristics. While the bactericidal property is expectedly induced, the elastic modulus as well as cell adhesion property remains uncompromised.

Item Type:	Journal Article
Publication:	INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
Publisher:	WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Additional Information:	Copyrightof this article belong to WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Department/Centre:	Division of Chemical Sciences > Materials Research Centre
Date Deposited:	09 Aug 2018 16:18
Last Modified:	25 Aug 2022 12:04
URI:	https://eprints.iisc.ac.in/id/eprint/60399

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