Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins

Sarkar, Rahul and Mitra, Sankash and Mukherjee, Santanu (2018) Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins. In: CHEMICAL SCIENCE, 9 (26). pp. 5767-5772.

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Abstract

The first iridium-catalyzed enantioselective vinylogous allylic alkylation of coumarins is presented. Using easily accessible linear allylic carbonates as the allylic electrophile, this reaction installs unfunctionalized allyl groups at the -position of 4-methylcoumarins in an exclusively branched-selective manner generally in high yields with an excellent level of enantioselectivity (up to 99:1 er).

Item Type:	Journal Article
Publication:	CHEMICAL SCIENCE
Publisher:	ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Additional Information:	Copyright of this article belong to ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	24 Jul 2018 14:54
Last Modified:	24 Jul 2018 14:54
URI:	http://eprints.iisc.ac.in/id/eprint/60279

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