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Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2O5 Nanomaterials

Ghosh, Sourav and Roy, Punarbasu and Karmodak, Naiwrit and Jemmis, Eluvathingal D and Mugesh, Govindasamy (2018) Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2O5 Nanomaterials. In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57 (17). pp. 4510-4515.

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Official URL: http://dx.doi.org/10.1002/anie.201800681

Abstract

Nanomaterials with enzyme-like activity (nanozymes) attract significant interest owing to their applications in biomedical research. Particularly, redox nanozymes that exhibit glutathione peroxidase (GPx)-like activity play important roles in cellular signaling by controlling the hydrogen peroxide (H2O2) level. Herein we report, for the first time, that the redox properties and GPx-like activity of V2O5 nanozyme depends not only on the size and morphology, but also on the crystal facets exposed on the surface within the same crystal system of the nanomaterials. These results suggest that the surface of the nanomaterials can be engineered to fine-tune their redox properties to act as nanoisozymes for specific biological applications.

Item Type: Journal Article
Publication: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Publisher: WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
Additional Information: Copy right for this article belong to WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
Department/Centre: Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited: 04 May 2018 18:49
Last Modified: 04 May 2018 18:49
URI: http://eprints.iisc.ac.in/id/eprint/59711

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