Spin-Noise-Detected Two-Dimensional Nuclear Magnetic Resonance at Triple Sensitivity

Ginthoer, Stephan J and Chandra, Kousik and Bechmann, Matthias and Rodin, Victor V and Mueller, Norbert (2018) Spin-Noise-Detected Two-Dimensional Nuclear Magnetic Resonance at Triple Sensitivity. In: CHEMPHYSCHEM, 19 (8). pp. 907-912.

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Abstract

A major breakthrough in speed and sensitivity of 2D spin-noise-detected NMR is achieved owing to a new acquisition and processing scheme called double block usage (DBU) that utilizes each recorded noise block in two independent cross-correlations. The mixing, evolution, and acquisition periods are repeated head-to-tail without any recovery delays and well-known building blocks of multidimensional NMR (constant-time evolution and quadrature detection in the indirect dimension as well as pulsed field gradients) provide further enhancement and artifact suppression. Modified timing of the receiver electronics eliminates spurious random excitation. We achieve a threefold sensitivity increase over the original snHMQC (spin-noise-detected heteronuclear multiple quantum correlation) experiment (K. Chandra etal., J. Phys. Chem. Lett. 2013, 4, 3853) and demonstrate the feasibility of spin-noise-detected long-range correlation.

Item Type:	Journal Article
Publication:	CHEMPHYSCHEM
Publisher:	WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
Additional Information:	Copy right for this article belong to WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
Department/Centre:	Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility)
Date Deposited:	04 May 2018 18:49
Last Modified:	04 May 2018 18:49
URI:	http://eprints.iisc.ac.in/id/eprint/59708

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