Reddy, Arava Amaranadha and Prasad, Kavirayani R (2017) Synthesis of beta-Amino Ketones by Addition of Aryl Methyl Ketones to Sulfinimines: Application to the Total Synthesis of HPA-12, Norsedamine, and Sedamine. In: JOURNAL OF ORGANIC CHEMISTRY, 82 (24). pp. 13488-13499.
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Official URL: http://dx.doi.org/10.1021/acs.joc.7b02611
Abstract
Synthesis of beta-sulfinamido ketones was accomplished by the addition of silyl enol ethers derived from arylmethyl ketones to chiral sulfinimines in excellent yield and selectivity. Application of the formed beta-amino substituted ketones is exemplified in the total synthesis of sphingolipid HPA-12 and the sedamine alkaloids.
| Item Type: | Journal Article |
|---|---|
| Publication: | JOURNAL OF ORGANIC CHEMISTRY |
| Publisher: | 10.1021/acs.joc.7b02611 |
| Additional Information: | Copy right for this article belongs to the AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 20 Jan 2018 06:20 |
| Last Modified: | 20 Jan 2018 06:20 |
| URI: | http://eprints.iisc.ac.in/id/eprint/58828 |
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