Polyelectrolyte multilayers for bio-applications: recent advancements

Pahal, Suman and Gakhar, Ruchi and Raichur, Ashok M and Varma, Manoj M (2017) Polyelectrolyte multilayers for bio-applications: recent advancements. In: IET NANOBIOTECHNOLOGY, 11 (8). pp. 903-908.

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Abstract

The synergistic relationship between structure and the bulk properties of polyelectrolyte multilayer (PEM) films has generated tremendous interest in their application for loading and release of bioactive species. Layer-by-layer assembly is the simplest, cost effective process for fabrication of such PEMs films, leading to one of the most widely accepted platforms for incorporating biological molecules with nanometre precision. The bulk reservoir properties of PEM films render them a potential candidate for applications such as biosensing, drug delivery and tissue engineering. Various biomolecules such as proteins, DNA, RNA or other desired molecules can be incorporated into the PEM stack via electrostatic interactions and various other secondary interactions such as hydrophobic interactions. The location and availability of the biological molecules within the PEM stack mediates its applicability in various fields of biomedical engineering such as programmed drug delivery. The development of advanced technologies for biomedical applications using PEM films has seen rapid progress recently. This review briefly summarises the recent successes of PEM being utilised for diverse bio-applications.

Item Type:	Editorials/Short Communications
Publication:	IET NANOBIOTECHNOLOGY
Additional Information:	Copy right for this article belongs to the INST ENGINEERING TECHNOLOGY-IET, MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD SG1 2AY, ENGLAND
Department/Centre:	Division of Mechanical Sciences > Materials Engineering (formerly Metallurgy) Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	26 Dec 2017 06:04
Last Modified:	26 Dec 2017 06:04
URI:	http://eprints.iisc.ac.in/id/eprint/58418

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