Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release

Sharma, Ajay Kumar and Nair, Mrutyunjay and Chauhan, Preeti and Gupta, Kavya and Saini, Deepak K and Chakrapani, Harinath (2017) Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release. In: ORGANIC LETTERS, 19 (18). pp. 4822-4825.

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Abstract

Generation of hydrogen sulfide (H2S) is challenging and few methods are capable of localized delivery of this gas. Here, a boron dipyrromethene-based carbamothioate (BDP-H2S) that is uncaged by visible light of 470 nm to generate carbonyl sulfide (COS), which is rapidly hydrolyzed to H2S in the presence of carbonic anhydrase, a widely prevalent enzyme, is reported.

Item Type:	Journal Article
Publication:	ORGANIC LETTERS
Additional Information:	Copy right for this article belongs to the AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited:	21 Oct 2017 06:18
Last Modified:	21 Oct 2017 06:18
URI:	http://eprints.iisc.ac.in/id/eprint/58060

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