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Insights on Heme Synthesis in the Malaria Parasite

Nagaraj, Viswanathan A and Padmanaban, Govindarajan (2017) Insights on Heme Synthesis in the Malaria Parasite. In: TRENDS IN PARASITOLOGY, 33 (8). pp. 583-586.

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Official URL: http://doi.org/10.1016/j.pt.2017.04.005


The malaria parasite has a functional heme-biosynthetic pathway, although it can access host hemoglobin-heme. The heme pathway is dispensable for blood stages, but essential in the mosquito stages which do not acquire hemoglobin-heme. We propose that the blood stage parasites maintain a dynamic heme pool through multiple back-up mechanisms.

Item Type: Editorials/Short Communications
Additional Information: Copy right for this article belongs to the ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 01 Sep 2017 09:05
Last Modified: 01 Sep 2017 09:05
URI: http://eprints.iisc.ac.in/id/eprint/57710

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