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Colorimetric sensors for rapid detection of various analytes

Piriya, Ajay VS and Joseph, Printo and Daniel, Kiruba SCG and Lakshmanan, Susithra and Kinoshita, Takatoshi and Muthusamy, Sivakumar (2017) Colorimetric sensors for rapid detection of various analytes. In: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 78 . pp. 1231-1245.

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Official URL: https://doi.org/10.1016/j.msec.2017.05.018


Sensor technology for the rapid detection of the analytes with high sensitivity and selectivity has several challenges. Despite the challenges, colorimetric sensors have been widely accepted for its high sensitive and selective response towards various analytes. In this review, colorimetric sensors for the detection of biomolecules like protein, DNA, pathogen and chemical compounds like heavy metal ions, toxic gases and organic compounds have been elaborately discussed. The visible sensing mechanism based on Surface Plasmon Resonance (SPR) using metal nanoparticles like Au, Ag, thin film interference using SiO2 and colorimetric array-based technique have been highlighted. The optical property of metal nanoparticles enables a visual color change during its interaction with the analytes owing to the dispersion and aggregation of nanoparticles. Recently, colorimetric changes using silica substrate for detection of protein and small molecules by thin film interference as a visible sensing mechanism has been developed without the usage of fluorescent or radioisotopes labels. Multilayer of biomaterials were used as a platform where reflection and interference of scattering light occur due to which color change happens leading to rapid sensing. Colorimetric array-based technique for the detection of organic compounds using chemoresponsive dyes has also been focused wherein the interaction of the analytes with the substrate coated with chemoresponsive dyes gives colorimetric change. (C) 2017 Elsevier B.V. All rights reserved.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Department/Centre: Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics
Date Deposited: 29 Jul 2017 07:21
Last Modified: 05 Mar 2019 05:53
URI: http://eprints.iisc.ac.in/id/eprint/57489

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