Illuminating Cyclic Nucleotides: Sensors for cAMP and cGMP and Their Application in Live Cell Imaging

Sharma, Suruchi and Visweswariah, Sandhya S (2017) Illuminating Cyclic Nucleotides: Sensors for cAMP and cGMP and Their Application in Live Cell Imaging. In: JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE, 97 (1). pp. 109-128.

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Abstract

Cyclic nucleotide monophosphates (cNMPs) act as second messengers in eukaryotic and prokaryotic signaling pathways. Even though cNMPs regulate a wide variety of processes, the effects they bring about can be highly specific, and are governed not just by the set of effectors present in a cell type, but also by upstream extracellular factors that modulate cNMP levels in the cell. Here, we describe various eukaryotic effectors of cAMP and cGMP and their use as tools to understand cNMP compartmentalization and temporal fluctuations inside cells.

Item Type:	Journal Article
Publication:	JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE
Additional Information:	Copy right for this article belongs to the INDIAN INST SCIENCE, INDIAN INST SCIENCE, BANGALORE 560012, INDIA
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited:	15 Jul 2017 07:22
Last Modified:	15 Jul 2017 07:22
URI:	http://eprints.iisc.ac.in/id/eprint/57411

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