Bagaria, A and Ramakumar, S and Gupta, M and Chauhan, VS (2005) Cyclo(L-leucyl-$\alpha$,$\beta$-dehydrophenylalanine): the first diketopiperazine containing an $\alpha$,$\beta$-dehydrophenylalanine residue. In: Acta crystallographica. Section C, Crystal structure communications, 61 (3). pp. 174-176.
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Abstract
The title compound (systematic name: 3-benzylidene-6-isobutylpiperazine-2,5-dione), $C_1_5H_1_8N_2O_2$, an $\alpha$,$\beta$-dehydrophenylalanine containing diketopiperazine, crystallizes in the space group P1 with two molecules in the asymmetric unit arranged antiparallel to one another. The $\alpha$,$\beta$-dehydrophenylalanine ($\Delta$Phe) residue in this cyclic peptide retains its planarity but deviates from the standard conformations observed in its linear analogues. Each type of molecule forms a linear chain with molecules of the same type via pairwise N-H \cdot\cdot\cdot O hydrogen bonds, while weaker C-H \cdot\cdot\cdot O interactions link the chains together to form a three-dimensional network.
Item Type: | Journal Article |
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Publication: | Acta crystallographica. Section C, Crystal structure communications |
Publisher: | International Union of Crystallography |
Additional Information: | The copyright belongs to International Union of Crystallography. |
Department/Centre: | Division of Information Sciences (Doesn't exist now) > BioInformatics Centre Division of Physical & Mathematical Sciences > Physics |
Date Deposited: | 27 Feb 2006 |
Last Modified: | 19 Sep 2010 04:24 |
URI: | http://eprints.iisc.ac.in/id/eprint/5671 |
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