Transfer hydrogenation reactions catalyzed by chiral half-sandwich Ruthenium complexes derived from Proline

Kumar, Arun Kumar Pandia and Samuelson, Ashoka G (2016) Transfer hydrogenation reactions catalyzed by chiral half-sandwich Ruthenium complexes derived from Proline. In: JOURNAL OF CHEMICAL SCIENCES, 128 (9). pp. 1405-1415.

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Abstract

Chiral ruthenium half-sandwich complexes were prepared using a chelating diamine made from proline with a phenyl, ethyl, or benzyl group, instead of hydrogen on one of the coordinating arms. Three of these complexes were obtained as single diastereoisomers and their configuration identified by X-ray crystallography. The complexes are recyclable catalysts for the reduction of ketones to chiral alcohols in water. A ruthenium hydride species is identified as the active species by NMR spectroscopy and isotopic labelling experiments. Maximum enantio-selectivity was attained when a phenyl group was directly attached to the primary amine on the diamine ligand derived from proline.

Item Type:	Journal Article
Publication:	JOURNAL OF CHEMICAL SCIENCES
Additional Information:	Copyrights belongs to this article to the INDIAN ACAD SCIENCES, C V RAMAN AVENUE, SADASHIVANAGAR, P B #8005, BANGALORE 560 080, INDIA
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	28 Oct 2016 07:19
Last Modified:	28 Oct 2016 07:19
URI:	http://eprints.iisc.ac.in/id/eprint/55153

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