Catalytic asymmetric formal gamma-allylation of deconjugated butenolides

Simlandy, Amit K and Mukherjee, Santanu (2016) Catalytic asymmetric formal gamma-allylation of deconjugated butenolides. In: ORGANIC & BIOMOLECULAR CHEMISTRY, 14 (24). pp. 5659-5664.

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Abstract

A formal gamma-allylation of deconjugated butenolides is reported based on a two-step sequence consisting of a catalytic diastereo- and enantioselective vinylogous nucleophilic addition to vinyl sulfones and Julia-Kocienski olefination. This highly modular approach delivers densely functionalized butenolides containing a quaternary stereogenic centre in excellent yield with high enantioselectivity.

Item Type:	Journal Article
Publication:	ORGANIC & BIOMOLECULAR CHEMISTRY
Publisher:	ROYAL SOC CHEMISTRY
Additional Information:	Copyright for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	25 Aug 2016 10:12
Last Modified:	25 Aug 2016 10:12
URI:	http://eprints.iisc.ac.in/id/eprint/54349

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